ABSTRACT
Objective To observe the therapeutic effect of spleen-invigorating and superficies-consolidating therapy combined with life style intervention for improving constitution of recurrent respiratory tract infection(RRTI) children.Methods One hundred and twenty RRTI children were classified into excessive yang with deficiency yin syndrome(N = 60) and excessive yin with deficiency yang syndrome(N = 60).Then the excessive yang with deficiency yin syndrome were equally randomized into herbal medicine group Ⅰ and western medicine group Ⅰ,and excessive yin with deficiency yang syndrome were equally randomized into herbal medicine group Ⅱ and western medicine group Ⅱ.Herbal medicine groups Ⅰ and Ⅱ were given Fuganning Oral Liquid and life style intervention,and western medicine groups Ⅰand Ⅱ were given thymic peptide capsules and life style intervention.Eight weeks constituted one treatment course.The score of symptoms before and after treatment,and the therapeutic effect were compared after 2 treatment courses.Results(1) The symptoms score was improved obviously in herbal medicine groups and western medicine groups(P 0.05).The difference of therapeutic effect was significant between both of herbal medicine groups(P
ABSTRACT
【Objective】To observe the effect of liguistrazine(Liz)on cerebral and serum monoamine neurotransmitter contents in spontaneous hypertension rats (SHR).【Methods】Twenty-four SHR rats were randomized into model group,hightdose Liz group(40 mg?kg-1?d-1),low-dose Liz group(20 mg?kg-1?d-1),and votalin group(4 mg?kg-1?d-1).The rats received gastric gavage of corresponding drugs according to the experimental design for 14 days.After treatment,the serum and hippocampal contents of dopamine,5-hydroxytryptamine and norepinephrine(NE)were detected with high performance liquid chromatography(HPLC).【Results】 High-and low-dose Liz markedly decreased cerebral NE content,increased serum and cerebral DA and 5-HT contents(P